Flu aandb

Flu aandb


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Influenza A and B infect humans each flu season and are both highly contagious. While treatment and prevention are the same, flu B tends to be less common. SearchUnderstanding the Different Types of Flu. Influenza is a respiratory infection caused by one of four different virus types: A, B, C, and D. Influenza is common worldwide, but only influenza types A and B cause seasonal epidemics. Influenza epidemics sometimes become pandemics, causing mass outbreaks of illness in humans around the world in a ...Different types of COVID-19 and flu test kits use different testing methodologies. They can either be antigen-based or use molecular techniques. Diagnostic tests for viral antigens or RNA indicate a current infection. Antigen Tests. Antigen assays typically detect nucleocapsid proteins from a virus like SARS-CoV-2 or Flu A+B.Influenza A and B: None: None: NPS in VTM: 3.5 hr: Moderate: Luminex: Verigene Respiratory Virus Nucleic Acid Test Plus: Verigene SP: Influenza A and B: H1, H1pdm09, H3: Respiratory Syncytial Virus (A, B) NPS in VTM: 3.5 hr: Moderate: Luminex: Verigene RP Flex: VERIGENE Reader VERIGENE Processor SP: Influenza A and B: H1/H1pdm09, H3 (SARS-CoV-2) (Coronavirus disease [COVID-19]), influenza virus types A and B, and respiratory syncytial virus, multiplex amplified probe technique Influenza/RSV and COVID-19 0240U Infectious disease (viral respiratory tract infection), pathogen-specific RNA, 3 targets (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], influenza A ...Yes, for some people. There are three flu vaccines that are preferentially recommended for people 65 years and older. These are Fluzone High-Dose Quadrivalent vaccine, Flublok Quadrivalent recombinant flu vaccine and Fluad Quadrivalent adjuvanted flu vaccine . This recommendation was based on a review of available studies which suggests that ...A healthcare professional may be able to test for COVID-19, the flu and RSV at the same visit. Abbott offers several diagnostic tools to aid in fast, reliable respiratory virus testing. From our ID-NOW™ rapid system to the Alinity m Resp-4-Plex to the Panbio COVID-19/Flu A&B Rapid Panel test*, we are equipping clinicians with tools to ...Waner JL, Todd, SI, Shalaby H, et al. Comparison of Directigen FLU-A with viral isolation and direct immunofluorescence for the rapid detection and identification of influenza A virus. J Clin Microbiol. 1991; 29(3):479-482. 2037665Influenza B almost exclusively infects humans and is less common than influenza A. Flu type B also mutates about two to three times more slowly than influenza A. Because humans are the natural host of influenza B, pandemics generally do not occur with influenza B viruses. 22. Although scientists can classify and monitor the different types of ... Oct 15, 2019 · There are four types of influenza virus: influenza A, B, C, and D. Types A and B are responsible for the flu epidemics that occur in the United States most winters. Influenza, or the flu, is a ... The flu is an infection of the nose, throat, and lungs. It spreads easily from person to person. This article discusses influenza types A and B. A type of influenza A infection due to the H1N1 influenza strain is commonly called the swine flu. Alternative NamesStrains of influenza B are exclusively contracted by humans, while A can be carried (and spread) by animals, however, both strains are transmitted mainly by respiratory droplets from coughing and contact with an infected person.Overview. Influenza virus testing is not required to make a clinical diagnosis of influenza in outpatients with suspected influenza, particularly during increased influenza activity when seasonal influenza A and B viruses are circulating in the local community. However, influenza virus testing can inform clinical management when the results may ... Rapid influenza diagnostic tests (RIDTs) detect influenza viral antigens in respiratory tract specimens. Available RIDTS detect and differentiate between type influenza A and B viruses, but do not specifically identify or differentiate subtypes of influenza A viruses. RIDTs are not recommended for use in hospitalized patients with suspected ...Information for the 2023-2024 Flu Season Thursday, August 17, 2023. CDC Reports Two Human Infections with Flu Viruses From Pigs Friday, August 4, 2023. H5N1 Bird Flu Found in Polish Domestic Cats Friday, July 21, 2023. Influenza Risk Assessment Tool (IRAT) Thursday, July 6, 2023. Virus Descriptions and Report Summaries Tuesday, July 4, 2023.The US is only about three months into the 2019–2020 flu season, and the illness has already left its mark—but it's a little different this year. According to the Centers for Disease Control ...For use with Sofia 2 and Sofia. The Sofia Influenza A+B Fluorescent Immunoassay (FIA) uses advanced immunofluorescence-based lateral-flow technology to detect influenza A and influenza B viral nucleoprotein antigens. Sofia 2 with Advance Result Technology (ART) delivers accurate, objective and automated results in as few as three minutes.Oct 15, 2019 · There are four types of influenza virus: influenza A, B, C, and D. Types A and B are responsible for the flu epidemics that occur in the United States most winters. Influenza, or the flu, is a ... Influenza A and B: None: None: NPS in VTM: 3.5 hr: Moderate: Luminex: Verigene Respiratory Virus Nucleic Acid Test Plus: Verigene SP: Influenza A and B: H1, H1pdm09, H3: Respiratory Syncytial Virus (A, B) NPS in VTM: 3.5 hr: Moderate: Luminex: Verigene RP Flex: VERIGENE Reader VERIGENE Processor SP: Influenza A and B: H1/H1pdm09, H3 Rapid assays for the diagnosis of influenza A and B viruses in patients evaluated at a large tertiary care children's hospital during two consecutive winter seasons. J Clin Virol. 2008;41(2):143-147. Cruz AT, Demmler-Harrison GJ, Caviness AC, et al. Performance of a rapid influenza test in children during the H1N1 2009 influenza a outbreak.Follow recommended infection prevention and control measures1. SARS-CoV-2 Testing. Test for SARS-CoV-2 by nucleic acid detection 2. , 3 ; OR if not available, by SARS-CoV-2 antigen detection assay. 5. a) If SARS-CoV-2 Test result is positive, administer supportive care. If the patient is at high risk for progression to severe COVID-19 ... Only type A and B cause human disease of any concern. Influenza virus is transmitted primarily by droplets or respiratory secretions of infected persons. Influenza occurs all over the world, with an annual global attack rate estimated at 5 – 10% in adults and 20 – 30% in children.People who are sick with flu often feel some or all of these symptoms: Fever*/feeling feverish or chills. Cough. Sore throat. Runny or stuffy nose. Muscle or body aches. Headaches. Fatigue (tiredness) Some people may have vomiting and diarrhea, though this is more common in children than adults.There are 4 types of influenza viruses, types A, B, C and D. Influenza A and B viruses circulate and cause seasonal epidemics of disease. Influenza A viruses are further classified into subtypes according to the combinations of the hemagglutinin (HA) and the neuraminidase (NA), the proteins on the surface of the virus. Currently circulating in ...Full genome sequencing can reveal the approximately 13,500-letter sequence of all the genes of the influenza virus’ genome. The two influenza types (A and B) that cause seasonal epidemics have eight RNA gene segments. These genes contain instructions for making new viruses and play an important role in how influenza viruses cause infection.There are four types of influenza virus: influenza A, B, C, and D. Types A and B are responsible for the flu epidemics that occur in the United States most winters. Influenza, or the flu, is a ...Aug 22, 2023 · FluNet Summary. This content is last updated on 22 August 2023. National Influenza Centres (NICs) and other national influenza laboratories from 108 countries, areas or territories reported data to FluNet for the time period from 24 July 2023 to 06 August 2023* (data as of 18/08/2023 06:58:57AM UTC). The WHO GISRS laboratories tested more than ... Yes, for some people. There are three flu vaccines that are preferentially recommended for people 65 years and older. These are Fluzone High-Dose Quadrivalent vaccine, Flublok Quadrivalent recombinant flu vaccine and Fluad Quadrivalent adjuvanted flu vaccine . This recommendation was based on a review of available studies which suggests that ...Jan 12, 2023 · Flu symptoms for both A and B tend to appear in progression, beginning with a sudden onset of fever. Other early symptoms include: Dry cough Runny nose Sore throat Body aches Headache Fatigue When young children acquire influenza, they may experience nausea, vomiting, or diarrhea in addition to respiratory symptoms. Rapid influenza diagnostic tests (RIDTs) detect influenza viral antigens in respiratory tract specimens. Available RIDTS detect and differentiate between type influenza A and B viruses, but do not specifically identify or differentiate subtypes of influenza A viruses. RIDTs are not recommended for use in hospitalized patients with suspected ...Influenza A and B: A(H1), A(H1)pdm09, A(H3) SARS-CoV-2, Adenovirus, Coronavirus 229E, Coronavirus HKU1, Coronavirus NL63, Coronavirus OC43, Human Metapneumovirus, Human Rhinovirus/Enterovirus, Parainfluenza Virus 1, Parainfluenza Virus 2, Parainfluenza Virus 3, Parainfluenza Virus 4, Respiratory Syncytial Virus: NPS: Approximately 45 minutes ... The last time the state saw a significant wave of influenza B was in 2019, when 12,950 cases of influenza B were recorded. In 2020, 720 notifications of influenza B were made. There were 57 in ...Doctors & departments Overview Flu (influenza) is an infection of the nose, throat and lungs, which are part of the respiratory system. Influenza is commonly called the flu, but it's not the same as stomach "flu" viruses that cause diarrhea and vomiting. Most people with the flu get better on their own.There are two main types of influenza viruses: types A and B. Both type A and B influenza viruses regularly spread in people and are responsible for seasonal flu each year. WHAT IS THESep 28, 2022 · Similarities: Both COVID-19 and flu can have varying degrees of symptoms, ranging from no symptoms (asymptomatic) to severe symptoms. Common symptoms that COVID-19 and flu share include: Fever or feeling feverish/having chills. Cough. Shortness of breath or difficulty breathing. During the 2020-2021 flu season, there was very low circulation of seasonal flu viruses. During September 27, 2020–May 22, 2021 in the United States, 1,899 (0.2%) of 1,081,671 clinical samples tested were positive for an influenza virus (713 [37.5%] influenza A and 1,186 [62.5%] influenza B). During that same period, public health ...There are three types of flu viruses: A, B, and C. Type A and B cause the annual influenza epidemics that have up to 20% of the population sniffling, aching, coughing, and running high...Feb 16, 2023 · indicate that influenza A and/or influenza B is likely, and diagnostic test results for other causes of illness (e.g., other respiratory illness) are negative. Influenza types A and B. These 2 types of viruses cause widespread illness (epidemics) almost every winter. They often lead to more people needing to go to the hospital, and more people dying from the flu. Public health officials focus on stopping the spread of types A and B. One of the reasons the flu remains a problem is because the viruses ...For influenza A and influenza B viruses, selective amplification of target nucleic acid from the sample is achieved by the use of target-specific forward and reverseTypes Symptoms Comparison Treatment Prevention Outlook There are four types of influenza virus. Influenza A is the most common, followed by influenza B. Both are highly contagious, and...Doctors & departments Overview Flu (influenza) is an infection of the nose, throat and lungs, which are part of the respiratory system. Influenza is commonly called the flu, but it's not the same as stomach "flu" viruses that cause diarrhea and vomiting. Most people with the flu get better on their own.Oct 15, 2019 · There are four types of influenza virus: influenza A, B, C, and D. Types A and B are responsible for the flu epidemics that occur in the United States most winters. Influenza, or the flu, is a ... Objectives Timely implementation of influenza infection control and treatment can significantly reduce the impact on Hospital resources and patient management when demand is at peak. Turnaround times of Laboratory based screening tests for the diagnosis of influenza may have an impact on the implementation of infection control measures and treatment. In this study the objectives included ...Yes. There are tests that will check for seasonal influenza A and B viruses and SARS-CoV-2, the virus that causes COVID-19. Testing for these viruses at the same time gives public health officials important information about how flu and COVID-19 are spreading and what prevention steps people should take.The assay targets the influenza A viruses (matrix gene), the influenza B viruses (matrix gene) and RSV (matrix gene). Results are reported as Detected or NOT detected and a semi-qualitative result is provided by reporting the PCR Cycle threshold (Ct) value for positive specimens. Note: Due to supply chain variables and logistical workflows to ...Rapid influenza diagnostic tests (RIDTs) RIDTs, also called flu antigen tests, are the most common type of flu test. They can identify the presence of influenza A and B, and they work by detecting the parts of the flu virus called antigens that trigger an immune response. RIDTs usually involve inserting a swab into your nostril to get a sample. Room temperature (15°C to 30°C/59°F to 86°F) Internal controls. Positive and negative included. External controls. Positive and negative included. PPA* (versus an FDA-cleared influenza A and B molecular assay) A: 81.5%, B: 80.9%. NPA* (versus an FDA-cleared influenza A and B molecular assay) A: 97.8%, B: 99.1%.Flu symptoms tend to develop one to two days after exposure to the virus and last for between five to seven days. Day 1 to Day 3 are characterized by the abrupt onset and worsening of symptoms. Day 5 to Day 6 is when most people start to feel notably better. By Day 8, most people will have recovered and no longer be contagious.For Influenza, the test demonstrated a positive percent agreement of 83.3% (Flu A) and 80% (Flu B) and a negative percent agreement of 97.5% (Flu A) and 95.3% (Flu B) versus RT-PCR, based on ...Doctors & departments Overview Flu (influenza) is an infection of the nose, throat and lungs, which are part of the respiratory system. Influenza is commonly called the flu, but it's not the same as stomach "flu" viruses that cause diarrhea and vomiting. Most people with the flu get better on their own.The assay targets the influenza A viruses (matrix gene), the influenza B viruses (matrix gene) and RSV (matrix gene). Results are reported as Detected or NOT detected and a semi-qualitative result is provided by reporting the PCR Cycle threshold (Ct) value for positive specimens. Note: Due to supply chain variables and logistical workflows to ...Flu symptoms for both A and B tend to appear in progression, beginning with a sudden onset of fever. Other early symptoms include: Dry cough Runny nose Sore throat Body aches Headache Fatigue When young children acquire influenza, they may experience nausea, vomiting, or diarrhea in addition to respiratory symptoms..
Influenza A viruses infect a range of mammalian (e.g. pigs and horses) and avian species, whereas type B and C infections are largely restricted to humans. Only types A and B cause human disease of any concern. All of the currently identified 16 HA and 9 NA subtypes of influenza A viruses are maintained in wild, aquatic bird populations.Feb 16, 2023 · indicate that influenza A and/or influenza B is likely, and diagnostic test results for other causes of illness (e.g., other respiratory illness) are negative. Nationally, flu activity during the 2021-2022 season began to increase in November and remained elevated until mid-June with two different waves of influenza A (H3N2) virus activity occurring; the first peaked in late December 2021, and the second in April 2022. Prior to the emergence of SARS-CoV-2, flu activity would most commonly begin to ...Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these ...Seasonal influenza (flu) vaccines are designed to protect against the four main groups of flu Type A and B viruses that research indicates are most likely to spread and cause illness among people during the upcoming flu season. All current U.S. flu vaccines protect against a flu A (H1) virus, a flu A (H3) virus, a flu B/Yamagata lineage virus ...Nov 7, 2022 · A healthcare professional may be able to test for COVID-19, the flu and RSV at the same visit. Abbott offers several diagnostic tools to aid in fast, reliable respiratory virus testing. From our ID-NOW™ rapid system to the Alinity m Resp-4-Plex to the Panbio COVID-19/Flu A&B Rapid Panel test*, we are equipping clinicians with tools to ... Dec 2, 2022 · Influenza (Flu) Viruses There are two main types of human flu viruses: types A and B. The flu A and B viruses that routinely spread in people are responsible for seasonal flu epidemics each year. Flu A viruses can be broken down into sub-types depending on the genes that make up the surface proteins. Mar 30, 2023 · There are four types of influenza viruses: A, B, C, and D. Influenza A and B viruses cause seasonal epidemics of disease in people (known as flu season) almost every winter in the United States. Influenza A viruses are the only influenza viruses known to cause flu pandemics (i.e., global epidemics of flu disease). The CDC’s website says you can get a flu shot and a COVID-19 shot at the same time --in the same arm or one in each arm--if that is convenient and you are due for vaccination, but they do not ...The assay targets the influenza A viruses (matrix gene), the influenza B viruses (matrix gene) and RSV (matrix gene). Results are reported as Detected or NOT detected and a semi-qualitative result is provided by reporting the PCR Cycle threshold (Ct) value for positive specimens. Note: Due to supply chain variables and logistical workflows to ... The fastest molecular flu test just got faster and even better. Now with early detection and positive results in as few as 5 minutes, allowing you to make effective clinical decisions sooner. Abbott ID NOW is a rapid, instrument-based system for the qualitative detection of infectious diseases using isothermal nucleic acid amplification technology.Types Symptoms Comparison Treatment Prevention Outlook There are four types of influenza virus. Influenza A is the most common, followed by influenza B. Both are highly contagious, and...Oct 9, 2020 · Influenza outbreaks are seen every year during the colder months of the year. Until now, four influenza pandemics have been reported, including the H1N1 (1918), the H2N2 (1957), the H3N2 (1967) and the H1N1 pandemic in 2009. 1 In addition, seasonal flu is reporting in different countries every year. Influenza mortality is associated with age ... Influenza B almost exclusively infects humans and is less common than influenza A. Flu type B also mutates about two to three times more slowly than influenza A. Because humans are the natural host of influenza B, pandemics generally do not occur with influenza B viruses. 22. Although scientists can classify and monitor the different types of ... Jun 28, 2018 · Abstract. Influenza is an infectious respiratory disease that, in humans, is caused by influenza A and influenza B viruses. Typically characterized by annual seasonal epidemics, sporadic pandemic ... The Flu SC2 Multiplex Assay and similar panels identify co-infections or alternative causes of influenza-like and COVID-19–like illnesses. The Flu SC2 Multiplex Assay can enable collection of critical data on influenza A and B viruses and SARS-CoV-2, as well as the prevalence of co-infection among these respiratory viruses.For influenza A and influenza B viruses, selective amplification of target nucleic acid from the sample is achieved by the use of target-specific forward and reverse As fears of a "tripledemic" die down, health officials say they are seeing an uptick of a particular strain of the flu: influenza B. According to data from the Centers for Disease Control and ...Background. Rapid influenza diagnostic tests (RIDTs) are immunoassays that can identify the presence of influenza A and B viral nucleoprotein antigens in respiratory specimens, and display the result in a qualitative way (positive vs. negative) (1). In the United States, a number of RIDTs are commercially available.Flu A and B cause the same types of symptoms, so it’s impossible to tell which variety you have from symptoms alone. Flu B symptoms can range from mild to severe. They often come on quickly and last for about a week.Full genome sequencing can reveal the approximately 13,500-letter sequence of all the genes of the influenza virus’ genome. The two influenza types (A and B) that cause seasonal epidemics have eight RNA gene segments. These genes contain instructions for making new viruses and play an important role in how influenza viruses cause infection.The flu is an infection of the nose, throat, and lungs. It spreads easily from person to person. This article discusses influenza types A and B. A type of influenza A infection due to the H1N1 influenza strain is commonly called the swine flu. Alternative NamesRapid influenza diagnostic tests (RIDTs) RIDTs, also called flu antigen tests, are the most common type of flu test. They can identify the presence of influenza A and B, and they work by detecting the parts of the flu virus called antigens that trigger an immune response. RIDTs usually involve inserting a swab into your nostril to get a sample.Rapid influenza diagnostic tests (RIDTs) detect influenza viral antigens in respiratory tract specimens. Available RIDTS detect and differentiate between type influenza A and B viruses, but do not specifically identify or differentiate subtypes of influenza A viruses. RIDTs are not recommended for use in hospitalized patients with suspected ...Rapid influenza diagnostic tests (RIDTs) RIDTs, also called flu antigen tests, are the most common type of flu test. They can identify the presence of influenza A and B, and they work by detecting the parts of the flu virus called antigens that trigger an immune response. RIDTs usually involve inserting a swab into your nostril to get a sample. Aug 22, 2023 · FluNet Summary. This content is last updated on 22 August 2023. National Influenza Centres (NICs) and other national influenza laboratories from 108 countries, areas or territories reported data to FluNet for the time period from 24 July 2023 to 06 August 2023* (data as of 18/08/2023 06:58:57AM UTC). The WHO GISRS laboratories tested more than ... Yes, for some people. There are three flu vaccines that are preferentially recommended for people 65 years and older. These are Fluzone High-Dose Quadrivalent vaccine, Flublok Quadrivalent recombinant flu vaccine and Fluad Quadrivalent adjuvanted flu vaccine . This recommendation was based on a review of available studies which suggests that ... The fastest molecular flu test just got faster and even better. Now with early detection and positive results in as few as 5 minutes, allowing you to make effective clinical decisions sooner. Abbott ID NOW is a rapid, instrument-based system for the qualitative detection of infectious diseases using isothermal nucleic acid amplification technology.(SARS-CoV-2) (Coronavirus disease [COVID-19]), influenza virus types A and B, and respiratory syncytial virus, multiplex amplified probe technique Influenza/RSV and COVID-19 0240U Infectious disease (viral respiratory tract infection), pathogen-specific RNA, 3 targets (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2], influenza A ... Oct 15, 2019 · The four types of influenza are A, B, C, and D. Types A and B are widespread during most winters in the United States. Type C is milder than types A or B and does not spread as easily. Type D ... Mar 10, 2020 · Objectives Timely implementation of influenza infection control and treatment can significantly reduce the impact on Hospital resources and patient management when demand is at peak. Turnaround times of Laboratory based screening tests for the diagnosis of influenza may have an impact on the implementation of infection control measures and treatment. In this study the objectives included ... for influenza A and B were not re-established with the modified device and may vary from previous performance. Performance characteristics may vary against other emerging influenza viruses. If ...For Influenza, the test demonstrated a positive percent agreement of 83.3% (Flu A) and 80% (Flu B) and a negative percent agreement of 97.5% (Flu A) and 95.3% (Flu B) versus RT-PCR, based on ...Information for the 2023-2024 Flu Season Thursday, August 17, 2023. CDC Reports Two Human Infections with Flu Viruses From Pigs Friday, August 4, 2023. H5N1 Bird Flu Found in Polish Domestic Cats Friday, July 21, 2023. Influenza Risk Assessment Tool (IRAT) Thursday, July 6, 2023. Virus Descriptions and Report Summaries Tuesday, July 4, 2023.Aug 22, 2023 · FluNet Summary. This content is last updated on 22 August 2023. National Influenza Centres (NICs) and other national influenza laboratories from 108 countries, areas or territories reported data to FluNet for the time period from 24 July 2023 to 06 August 2023* (data as of 18/08/2023 06:58:57AM UTC). The WHO GISRS laboratories tested more than ... The fastest molecular flu test just got faster and even better. Now with early detection and positive results in as few as 5 minutes, allowing you to make effective clinical decisions sooner. Abbott ID NOW is a rapid, instrument-based system for the qualitative detection of infectious diseases using isothermal nucleic acid amplification technology.May 28, 2009 · Influenza A viruses infect a range of mammalian (e.g. pigs and horses) and avian species, whereas type B and C infections are largely restricted to humans. Only types A and B cause human disease of any concern. All of the currently identified 16 HA and 9 NA subtypes of influenza A viruses are maintained in wild, aquatic bird populations. types of influenza viruses: A, B, and C. Type A viruses are the most prevalent and are associated with most serious epidemics. Type B viruses produce a disease that is generally milder than that caused by type A. Type C viruses have never been associated with a large epidemic of human disease. Both type A and B viruses canInfluenza — commonly known as the flu — is a respiratory infection caused by flu viruses. There are three main types of influenza: A, B, and C. Types A and B are similar, but influenza B can ...Flu A and B cause the same types of symptoms, so it’s impossible to tell which variety you have from symptoms alone. Flu B symptoms can range from mild to severe. They often come on quickly and last for about a week.Oct 9, 2020 · Influenza outbreaks are seen every year during the colder months of the year. Until now, four influenza pandemics have been reported, including the H1N1 (1918), the H2N2 (1957), the H3N2 (1967) and the H1N1 pandemic in 2009. 1 In addition, seasonal flu is reporting in different countries every year. Influenza mortality is associated with age ... cough. sore throat. runny or stuffy nose. muscle or body aches. headaches. fatigue (tiredness) some people may have vomiting and diarrhea, though this is more common in children than adults. *It’s important to note that not everyone with flu will have a fever. More information is available at Flu and COVID-19 symptoms.serious flu complications. There are two main types of . influenza viruses: types A and B. Both type A and B . influenza viruses regularly spread in people, and are . responsible for seasonal flu ...

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